Although NIR is primarily used in production-related applications, it has found great utility in research and development facilities. Pharmaceutical R&D often uses NIR in pilot plants operations to help evaluate daily processes. Work is being done to understand blend uniformity, granulation drying, dissolution profile prediction and lyophilization processes. Chemical R&D facilities use NIR to optimize process performance and product quality.
Common R&D NIR parameters measured include: moisture content, coating thickness, roller compaction hardness, blend uniformity, granulation, particle size and prediction of dissolution profile.
Downloads:
- Analysis of Residual Moisture in a Lyophilized Pharmaceutical Product by NIR Spectroscopy
- A Guide to Near-Infrared Spectroscopic Analysis of Industrial Manufacturing
Processes - Near-Infrared Absorptions
Links to Analyzers:
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XDS Rapid Content Analyzer (RCA) The FOSS Rapid Content® Analyzer, based on XDS near-infrared technology, provides the next generation of dedicated NIR analysis for rapid non-destructive measurements of solid and liquid chemical and pharmaceutical formulations. Read more... |
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XDS Rapid Liquid Analyzer (RLA) The FOSS Rapid Liquid™ Analyzer provides rapid non-destructive NIR analysis of liquid chemical and pharmaceutical formulations. Read more... |
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XDS Process Analytics MicroBundle Analyzers FOSS' Process analyzers are used throughout the process stream to ensure optimum performance for widely varying samples. The 80-fiber count (40 illumination / 40 collection fibers) allows for cost-effective analysis of sample types ranging from clear liquids to suspensions and solids. Read more... |
